Along with Reactome's events hierarchy, This function will retrieve all the events beginning from your supplied event up to the "Top level Pathway". see "Details section" for more information.
Arguments
- event_id
Character: Reactome event's identifier.
- ...
rbioapi option(s). See
rba_options's arguments manual for more information on available options.
Value
List which every element is a Data frame listing your supplied event along with it's ancestor events. Because any given event can be part of more than one pathway hierarchy, the list may contain multiple data frames.
Details
By Reactome's definition, Events are the building blocks of biological processes and could be of two main classes: "Pathway" or "Reaction-like events". The events are organized in a hierarchical structure; and each event could be child or parent to another event; The hierarchy will always begin with a "Top level pathway" event. Also note that a given event could be part of more that one hierarchies.
References
Ragueneau, E., Gong, C., Sinquin, P., Sevilla, C., Beavers, D., Grentner, A., ... D’Eustachio, P. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Res., 54(D1), D673–D681. doi: 10.1093/nar/gkaf1223
Griss, J., Viteri, G., Sidiropoulos, K., Nguyen, V., Fabregat, A., & Hermjakob, H. (2020). ReactomeGSA—Efficient Multi-Omics Comparative Pathway Analysis. Molecular & Cellular Proteomics, 19(12), 2115–2125. doi: 10.1074/mcp.TIR120.002155
See also
Other "Reactome Content Service - Queries Related to Events":
rba_reactome_event_hierarchy()