You can call this function in two scenarios: 1- To retrieve information of all available PSICQUIC resources, call the function without providing any argument; i.e rba_reactome_interactors_psicquic(). 2-To retrieve a list of interactors of specific protein(s), fill out the function's arguments.

rba_reactome_interactors_psicquic(
  proteins = NULL,
  resource = NULL,
  details = TRUE,
  ...
)

Arguments

proteins

Proteins to retrieve PSICQUIC interactors.

resource

The PSICQUIC resource for your supplied proteins. Call rba_reactome_interactors_psicquic() without argument to get the available options.

details

Logical: If TRUE (default) a detailed list of interactors will be returned. If FALSE, only a summary of available interactors will be returned.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

Depending your input, a list containing the detailed or summary of PSICQUIC interactions or a data frame of all registered PSICQUIC resources.

Corresponding API Resources

"POST https://reactome.org/ContentService/interactors/psicquic/molecules/ resource/details" "POST https://reactome.org/ContentService/interactors/psicquic/molecules/ resource/summary" "GET https://reactome.org/ContentService/interactors/psicquic/resources"

References

  • Jassal B, Matthews L, Viteri G, Gong C, Lorente P, Fabregat A, Sidiropoulos K, Cook J, Gillespie M, Haw R, Loney F, May B, Milacic M, Rothfels K, Sevilla C, Shamovsky V, Shorser S, Varusai T, Weiser J, Wu G, Stein L, Hermjakob H, D'Eustachio P. The reactome pathway knowledgebase. Nucleic Acids Res. 2020 Jan 8;48(D1):D498-D503. doi: 10.1093/nar/gkz1031. PubMed PMID: 31691815.

  • Reactome Content Services API Documentation

See also

Other "Reactome Content Service - Molecule Interactors": rba_reactome_interactors_static()

Examples

# \donttest{
rba_reactome_interactors_psicquic()
# }
# \donttest{
rba_reactome_interactors_psicquic(proteins = c("TP53", "MYC"),
    resource = "BioGrid",
    details = FALSE)
# }
# \donttest{
rba_reactome_interactors_psicquic(proteins = c("TP53", "MYC"),
    resource = "BioGrid",
    details = TRUE)
# }