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The interface From Reactome to PSICQUIC

Source: R/reactome_content.R
rba_reactome_interactors_psicquic.Rd

You can call this function in two scenarios: 1- To retrieve information of all available PSICQUIC resources, call the function without providing any argument; i.e rba_reactome_interactors_psicquic(). 2-To retrieve a list of interactors of specific protein(s), fill out the function's arguments.

Usage

rba_reactome_interactors_psicquic(
  proteins = NULL,
  resource = NULL,
  details = TRUE,
  ...
)

Arguments

proteins

Character or Numeric vector: (optional) Proteins to retrieve PSICQUIC interactors.

resource

Character: (optional) The PSICQUIC resource for your supplied proteins. Call rba_reactome_interactors_psicquic() without argument to get the available options.

details

Logical: (default = TRUE) If TRUE a detailed list of interactors will be returned. If FALSE, only a summary of available interactors will be returned.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

Depending your input, a list containing the detailed or summary of PSICQUIC interactions or a data frame of all registered PSICQUIC resources.

Corresponding API Resources

"POST https://reactome.org/ContentService/interactors/psicquic/molecules/ {resource}/details"
"POST https://reactome.org/ContentService/interactors/psicquic/molecules/ {resource}/summary"
"GET https://reactome.org/ContentService/interactors/psicquic/resources"

References

  • Ragueneau, E., Gong, C., Sinquin, P., Sevilla, C., Beavers, D., Grentner, A., ... D’Eustachio, P. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Res., 54(D1), D673–D681. doi: 10.1093/nar/gkaf1223

  • Griss J, Viteri G, Sidiropoulos K, Nguyen V, Fabregat A, Hermjakob H. ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis. Mol Cell Proteomics. 2020 Sep 9. doi: 10.1074/mcp. PubMed PMID: 32907876.

  • Reactome Content Services API Documentation

  • Citations note on Reactome website

See also

Other "Reactome Content Service - Molecule Interactors": rba_reactome_interactors_static()

Examples

# \donttest{
rba_reactome_interactors_psicquic()
# }
# \donttest{
rba_reactome_interactors_psicquic(proteins = c("TP53", "MYC"),
    resource = "BioGrid",
    details = FALSE)
# }
# \donttest{
rba_reactome_interactors_psicquic(proteins = c("TP53", "MYC"),
    resource = "BioGrid",
    details = TRUE)
# }