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UniProt describes how sequence mutations affect the biological properties of a protein, cell, or organism. Retrieve the mutagenesis annotations mapped to one UniProt protein.

Usage

rba_uniprot_mutagenesis(accession, location = NULL, ...)

Arguments

accession

Character: UniProtKB primary or secondary accession.

location

Character: (optional) A valid amino acid range (e.g. 10-25) within the sequence of the given protein.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

A list containing the mutagenesis description of your supplied UniProt protein's sequence.

Corresponding API Resources

"GET https://www.ebi.ac.uk/proteins/api/mutagenesis/{accession}"

References

  • The UniProt Consortium. (2025). UniProt: the Universal Protein Knowledgebase in 2025. Nucleic Acids Research, 53(D1), D609–D617. https://doi.org/10.1093/nar/gkae1010

  • Nightingale, A., Antunes, R., Alpi, E., Bursteinas, B., Gonzales, L., Liu, W., Luo, J., Qi, G., Turner, E., & Martin, M. (2017). The Proteins API: Accessing key integrated protein and genome information. Nucleic Acids Research, 45(W1), W539–W544. https://doi.org/10.1093/nar/gkx237

  • Proteins API Documentation

  • Citations note on UniProt website

See also

Other "UniProt - Mutagenesis": rba_uniprot_mutagenesis_search()

Examples

# \donttest{
rba_uniprot_mutagenesis(accession = "P0DTC2", location = "300-400")
# }