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UniProt describes the effects of mutations in proteins' amino acid sequence on the biological properties of the protein, cell or the organism. Using this function, you can get the Mutagenesis description that has been mapped to a given UniProt protein.


rba_uniprot_mutagenesis(accession, location = NULL, ...)



UniProtKB primary or secondary accession(s).


A valid amino acid range (e.g. 10-25) within the sequence range of the given proein.


rbioapi option(s). See rba_options's arguments manual for more information on available options.


A list containing the mutagenesis description of your supplied UniProt protein's sequence.

Corresponding API Resources



  • The UniProt Consortium, UniProt: the universal protein knowledgebase in 2021, Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D480–D489,

  • Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd Turner, Maria Martin, The Proteins API: accessing key integrated protein and genome information, Nucleic Acids Research, Volume 45, Issue W1, 3 July 2017, Pages W539–W544,

  • Proteins API Documentation

  • Citations note on UniProt website

See also

Other "UniProt - Mutagenesis": rba_uniprot_mutagenesis_search()


# \donttest{
rba_uniprot_mutagenesis(accession = "P0DTC2", location = "300-400")
# }