Search Mutagenesis in UniProt

UniProt describes how sequence mutations affect the biological properties of a protein, cell, or organism. Use this function to search for mutagenesis annotations using at least one of accession, taxid, or db_id.

Usage

rba_uniprot_mutagenesis_search(
  accession = NULL,
  taxid = NULL,
  db_id = NULL,
  ...
)

Arguments

accession

Character: (optional) UniProtKB primary or secondary accession(s). You can supply up to 100 accession numbers.

taxid

Numeric: (optional) NIH-NCBI Taxon ID. You can supply up to 20 taxon IDs.

db_id

Character: (optional) The ID in a cross-reference database. You can supply up to 20 values.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

A list in which each element represents a matching UniProt entry, named by accession when available. Mutagenesis annotations are stored in the entry's features element.

Corresponding API Resources

"GET https://www.ebi.ac.uk/proteins/api/mutagenesis"

References

• The UniProt Consortium. (2025). UniProt: the Universal Protein Knowledgebase in 2025. Nucleic Acids Research, 53(D1), D609–D617. https://doi.org/10.1093/nar/gkae1010

• Nightingale, A., Antunes, R., Alpi, E., Bursteinas, B., Gonzales, L., Liu, W., Luo, J., Qi, G., Turner, E., & Martin, M. (2017). The Proteins API: Accessing key integrated protein and genome information. Nucleic Acids Research, 45(W1), W539–W544. https://doi.org/10.1093/nar/gkx237

• Proteins API Documentation

• Citations note on UniProt website

See also

Other "UniProt - Mutagenesis": rba_uniprot_mutagenesis()

Examples

# \donttest{
#search all mutations in COVID19 proteins
rba_uniprot_mutagenesis_search(taxid = 2697049)
# }