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UniProt describes the effects of mutations in proteins' amino acid sequence on the biological properties of the protein, cell or the organism. Using this function, you can search for mutagenesis description in UniProt proteins. You may also refine your search. See "Arguments section" for more information.

Usage

rba_uniprot_mutagenesis_search(
  accession = NULL,
  taxid = NULL,
  db_id = NULL,
  ...
)

Arguments

accession

UniProtKB primary or secondary accession(s). You can supply up to 100 accession numbers.

taxid

NIH-NCBI Taxon ID. You can supply up to 20 taxon IDs.

db_id

The ID in a Cross-reference (external) database. You can supply up to 20 values.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

A list Where each element correspond to a UniProt protein (search hit) and mutagenesis description are organized under the "features" sub-list.

Details

Note that this is a search function. Thus, you are not required to fill every argument; You may use whatever combinations of arguments you see fit for your query.

Corresponding API Resources

"GET https://www.ebi.ac.uk/proteins/api/mutagenesis"

References

  • The UniProt Consortium, UniProt: the universal protein knowledgebase in 2021, Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D480–D489, https://doi.org/10.1093/nar/gkaa1100

  • Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd Turner, Maria Martin, The Proteins API: accessing key integrated protein and genome information, Nucleic Acids Research, Volume 45, Issue W1, 3 July 2017, Pages W539–W544, https://doi.org/10.1093/nar/gkx237

  • Proteins API Documentation

  • Citations note on UniProt website

See also

Other "UniProt - Mutagenesis": rba_uniprot_mutagenesis()

Examples

# \donttest{
#search all mutations in COVID19 proteins
rba_uniprot_mutagenesis_search(taxid = 2697049)
# }