Get UniProt Entry by UniProt Cross-Reference Database and ID

UniProt cross-references connect protein entries with identifiers in external databases. Retrieve UniProtKB entries associated with an identifier from one of these databases.

Usage

rba_uniprot_proteins_crossref(
  db_id,
  db_name,
  reviewed = NULL,
  isoform = NULL,
  ...
)

Arguments

db_id

Character: Protein identifier in the cross-reference database.

db_name

Character: Cross-reference database name.

reviewed

Logical: (optional) If TRUE, return only reviewed Swiss-Prot entries. If FALSE, return only unreviewed TrEMBL entries.

isoform

Numeric: (optional) One of:

0: Exclude isoforms.
1: Return isoforms only.

See alternative products.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

A list named by UniProt accession. Each element is a UniProtKB entry corresponding to the supplied cross-reference identifier.

Corresponding API Resources

"GET https://www.ebi.ac.uk/proteins/api/proteins/{dbtype}:{dbid}"

References

The UniProt Consortium. (2025). UniProt: the Universal Protein Knowledgebase in 2025. Nucleic Acids Research, 53(D1), D609–D617. https://doi.org/10.1093/nar/gkae1010
Nightingale, A., Antunes, R., Alpi, E., Bursteinas, B., Gonzales, L., Liu, W., Luo, J., Qi, G., Turner, E., & Martin, M. (2017). The Proteins API: Accessing key integrated protein and genome information. Nucleic Acids Research, 45(W1), W539–W544. https://doi.org/10.1093/nar/gkx237
Proteins API Documentation
Citations note on UniProt website

Examples

# \donttest{
rba_uniprot_proteins_crossref("cd40", "hgnc")
# }
# \donttest{
rba_uniprot_proteins_crossref("cd40", "hgnc", reviewed = TRUE)
# }
# \donttest{
rba_uniprot_proteins_crossref("mica", "hgnc", isoform = 0)
# }