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Get Post-Translational Modification of UniProt Protein

Source: R/uniprot_proteomics.R
rba_uniprot_proteomics_ptm.Rd

UniProt maps post-translational modification proteomics data from different sources to the proteins' sequences. Using this function, you can retrieve all the post-translational-modification features mapped to a given UniProt protein's sequence.

Usage

rba_uniprot_proteomics_ptm(accession, confidence_score = NULL, ...)

Arguments

accession

Character: UniProtKB primary or secondary accession.

confidence_score

Character: (optional) One or more of "Bronze", "Silver", or "Gold"; you can supply all three values. UniProt classifies modified residues by false localization rate across multiple datasets. See Large-scale modified residues for more information.

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

A list containing the post-translational modification features of your supplied UniProt protein's sequence.

Details

see also: PTM / Processing section in UniProtKB

UniProt categorizes proteomics data sources into three main data categories: PTM (Post-Translational Modification), non-PTM, and HPP (Human Proteome Project); each with corresponding API endpoints, and thus, rbioapi functions.

Corresponding API Resources

"GET https://www.ebi.ac.uk/proteins/api/proteomics/ptm/{accession}"

References

  • The UniProt Consortium. (2025). UniProt: the Universal Protein Knowledgebase in 2025. Nucleic Acids Research, 53(D1), D609–D617. https://doi.org/10.1093/nar/gkae1010

  • Nightingale, A., Antunes, R., Alpi, E., Bursteinas, B., Gonzales, L., Liu, W., Luo, J., Qi, G., Turner, E., & Martin, M. (2017). The Proteins API: Accessing key integrated protein and genome information. Nucleic Acids Research, 45(W1), W539–W544. https://doi.org/10.1093/nar/gkx237

  • Proteins API Documentation

  • Citations note on UniProt website

See also

Other "UniProt - Proteomics": rba_uniprot_proteomics_hpp(), rba_uniprot_proteomics_hpp_search(), rba_uniprot_proteomics_non_ptm(), rba_uniprot_proteomics_non_ptm_search(), rba_uniprot_proteomics_ptm_search(), rba_uniprot_proteomics_species()

Examples

# \donttest{
  rba_uniprot_proteomics_ptm(accession = "P04234")
# }