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This function will return a list of subunits which are participants of your supplied complex.

Usage

rba_reactome_complex_subunits(complex_id, exclude_structures = FALSE, ...)

Arguments

complex_id

Reactome stable Identifier of the complex.

exclude_structures

(logical) Should the contained complexes and entity sets be excluded from the results? (default = FALSE)

...

rbioapi option(s). See rba_options's arguments manual for more information on available options.

Value

Data frame which each row is a subunit of your supplied complex and the columns are pertinent information of that subunit.

Details

Subunits will be returned recursively; Which means that if a subunit was itself a complex, subunit of that complex will be also returned in the results.

Corresponding API Resources

"GET https://reactome.org/ContentService/data/complex/id/subunits"

References

  • Marc Gillespie, Bijay Jassal, Ralf Stephan, Marija Milacic, Karen Rothfels, Andrea Senff-Ribeiro, Johannes Griss, Cristoffer Sevilla, Lisa Matthews, Chuqiao Gong, Chuan Deng, Thawfeek Varusai, Eliot Ragueneau, Yusra Haider, Bruce May, Veronica Shamovsky, Joel Weiser, Timothy Brunson, Nasim Sanati, Liam Beckman, Xiang Shao, Antonio Fabregat, Konstantinos Sidiropoulos, Julieth Murillo, Guilherme Viteri, Justin Cook, Solomon Shorser, Gary Bader, Emek Demir, Chris Sander, Robin Haw, Guanming Wu, Lincoln Stein, Henning Hermjakob, Peter D’Eustachio, The reactome pathway knowledgebase 2022, Nucleic Acids Research, 2021;, kab1028, https://doi.org/10.1093/nar/gkab1028

  • Griss J, Viteri G, Sidiropoulos K, Nguyen V, Fabregat A, Hermjakob H. ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis. Mol Cell Proteomics. 2020 Sep 9. doi: 10.1074/mcp. PubMed PMID: 32907876.

  • Reactome Content Services API Documentation

  • Citations note on Reactome website

See also

Other "Reactome Content Service - Physical Entity Queries": rba_reactome_complex_list(), rba_reactome_entity_other_forms(), rba_reactome_participant_of()

Examples

# \donttest{
rba_reactome_complex_subunits(complex_id = "R-HSA-5674003",
    exclude_structures = FALSE)
# }
# \donttest{
rba_reactome_complex_subunits(complex_id = "R-HSA-109783",
    exclude_structures = TRUE)
# }